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Alzheimer Dementia, sporadic, association marker ACE

Neurology 10.005

Alzheimer Dementia, sporadic, association marker ACE

AD2
Signs/symptoms: Dementia, late onset, sporadic
Complications: Neuritic plaques and neurons with neurofibrillary tangles.
Early diagnosis/treatment: Yes
Association between homozygosity for both the ACE I and D allele polymorphisms and Alzheimer's disease (AD).

Material required:
Blood tubes: EDTA whole blood (do not freeze, do not centrifugate)
Mouth brush: Yes
Chromosomal localization: 17q23 OMIM number: 106180

Angiotensin I converting enzyme (insertions/deletions polymorphism)

ACE

Gene regions tested:
Gene regions:
Amino acid positions: insertion/deletion polymorphism
Nucleotide positions:
Test methods: Sequencing

Prices:

Switzerland:
8820.00 8811.01 8819.01
  TP REVAL: 250 TP Value: 0.9 CHF 225.00
Other europe: EUR 160.00
Other regions: USD call

References:
Narain Y, Yip A, Murphy T, Brayne C, Easton D, Evans JG, Xuereb J, Cairns N, Esiri MM, Furlong RA, Rubinsztein DC. The ACE gene and Alzheimer's disease susceptibility. J. Med. Genet. 37:695-697,2000.

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